CsiCon Las Vegas
I love CsiCon. It's a chance to go listen to some of my favorite scientists and thinkers speak on a wide variety of topics. The conference itself is hosted by The Committee for Skeptical Inquiry, which promote critical thinking and science education.
The conference has recently settled in Las Vegas and brings in a number or renowned researchers, podcasters, and science communicators to expound on the need for passionate discussion and communication of scientific principles. More info on the conference at csiconference.org.